CD35 / RealBlue 545 / E11

Product Details
Supplier BD Biosciences
Catalog #: 756636 (View supplier product page)
Size 50 μg
Price $422.00
Antigen CD35
Clone E11
Host Mouse
Isotype IgG1 κ
Conjugate RealBlue 545
Target Species Human
Applications FC
Description Hu CD35 RB545 E11 50ug
About CD35 and RealBlue 545
CD35 This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The genome is polymorphic at this locus with allele-specific splice variants encoding different isoforms, based on the presence/absence of long homologous repeats (LHRs). The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in this gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus, sarcoidosis and Alzheimer's disease. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. [provided by RefSeq, May 2020]
RealBlue 545 BD Horizon RealBlue™ 545 (RB545) is part of BD's new product line of laser-specific fluorochromes which are designed to minimize cross laser excitaiton. This fluorochrome has a maximum excitation wavelength of 496nm and a maximum emission wavelength of 545nm. While RB545 is excited by the 488nm blue laser, it offers miminal cross-laser excitation off of the 561nm yellow/green laser. It is designed for use in Flow Cytometry and Spectral Flow Cytometry.
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RealBlue 545 Excitation and Emission Spectra