p53 / mFluor Violet 610 / SPM590

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-34434MFV610 (View supplier product page)
Size 100 μl
Price $679.00
Antigen p53
Clone SPM590
Host Mouse
Isotype IgG2b κ
Conjugate mFluor Violet 610
Target Species Bovine, Human, Monkey
Applications FC
Description p53 Antibody (SPM590) [mFluor Violet 610 SE]
About p53 and mFluor Violet 610
p53 This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
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Reviews & Ratings
mFluor Violet 610 Excitation and Emission Spectra