Arginase 1 / PerCP / 658922
Arginase 1 / PerCP / 658922
Citations:
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Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | IC8026C (View supplier product page) | |
| Size | 100 Tests | |
| Price | $469.00 | |
| Antigen | Arginase 1 | |
| Clone | 658922 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | PerCP | |
| Target Species | Human | |
| Applications | ICS | |
| Description | Human Arginase 1/ARG1 PerCP-conjugated Antibody |
About Arginase 1 and PerCP
| Arginase 1 | Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] | |
|---|---|---|
| PerCP | Peridinin-Chlorophyll-Protein (PerCP) is a red-emitting fluorescent protein isolated from algae that can be excited by the 488 nm blue laser and captured with a 670/30 nm bandpass filter. PerCP exhibits a large Stokes' Shift, with an excitation peak at 482 nm and an emission peak at 675 nm. PerCP is was historically used in flow cytometry, however it is highly susceptible to photobleaching and has poor stability. Alternatives like BB700, NovaFluor Blue 690 or PerCP-eFluor™ 710 are preferred. PerCP is a generic dye that has no sole manufacturer. |
Images
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Detection of Arginase 1/ARG1 in HepG2 Human Cell Line by Flow Cytometry. HepG2 human hepatocellular carcinoma cell line was stained with Mouse Anti-Human Arginase 1/ARG1 PerCP-conjugated Monoclonal Antibody (Catalog # IC8026C, filled histogram) or isotype control antibody (Catalog # IC0041C, open histogram). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005). View our protocol for Staining Intracellular Molecules. |
Citations
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PerCP Excitation and Emission Spectra
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