CD324 / mFluor Violet 450 / CDH1/1525

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-54551MFV450 (View supplier product page)
Size 100 μl
Price $709.00
Antigen CD324
Clone CDH1/1525
Host Mouse
Isotype IgG1 κ
Conjugate mFluor Violet 450
Target Species Human, Mouse
Applications FC
Description E-Cadherin Antibody (CDH1/1525) [mFluor Violet 450 SE]
About CD324 and mFluor Violet 450
CD324 This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015]
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mFluor Violet 450 Excitation and Emission Spectra