CD59 / mFluor Violet 610 / MACIF/629

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-47820MFV610 (View supplier product page)
Size 100 μl
Price $679.00
Antigen CD59
Clone MACIF/629
Host Mouse
Isotype IgG1 κ
Conjugate mFluor Violet 610
Target Species Human
Applications FC
Description CD59 Antibody (MACIF/629) [mFluor Violet 610 SE]
About CD59 and mFluor Violet 610
CD59 This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
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mFluor Violet 610 Excitation and Emission Spectra