MCP-1 / mFluor Violet 450 / 2D8

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-22115MFV450 (View supplier product page)
Size 100 μl
Price $569.00
Antigen MCP-1
Clone 2D8
Host Mouse
Isotype IgG1
Conjugate mFluor Violet 450
Target Species Feline, Human, Mouse, Primate, Rat
Applications FC
Description CCL2/MCP1 Antibody (2D8) [mFluor Violet 450 SE]
About MCP-1 and mFluor Violet 450
MCP-1 This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. [provided by RefSeq, Aug 2020]
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mFluor Violet 450 Excitation and Emission Spectra