CD137L / mFluor Violet 500 / TKS-1

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-81115MFV500 (View supplier product page)
Size 100 μl
Price $519.00
Antigen CD137L
Clone TKS-1
Host Rabbit
Isotype IgG κ
Conjugate mFluor Violet 500
Target Species Mouse
Applications FC
Description 4-1BB Ligand/TNFSF9 Antibody (TKS-1) [mFluor Violet 500 SE]
About CD137L and mFluor Violet 500
CD137L The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided by RefSeq, Oct 2008]
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mFluor Violet 500 Excitation and Emission Spectra