CLEC2 / PE-Cy7 / 17D9/CLEC-2

Product Details
Supplier BioLegend
Catalog #: 146107 (View supplier product page)
Size 25 μg
Price $176.00
Antigen CLEC2
Clone 17D9/CLEC-2
Host Rat
Isotype IgG2b κ
Conjugate PE-Cy7
Target Species Mouse
Applications FC
Description PE/Cyanine7 anti-mouse CLEC-2 (CLEC1B)
About CLEC2 and PE-Cy7
CLEC2 Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011]
PE-Cy7 PE-Cyanine®7 (PE-Cy7, RPE-Cy7) is a far red-emitting tandem fluorophore that combines phycoerythrin (PE) and Cy7. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Cy7, which emits light that can be captured with a 780/60 nm bandpass filter. PE-CY7 has an excitation peak at 565 nm and an emission peak at 778 nm, and is a suitable alternative to PE-Vio®770 (Miltenyi) and cFluor BYG781 (Cytek).
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PE-Cy7 Excitation and Emission Spectra