Desmoglein-2 / Brilliant Violet 510 / 6D8

Product Details
Supplier BD Biosciences
Catalog #: 755137 (View supplier product page)
Size 50 μg
Price $524.00
Antigen Desmoglein-2
Clone 6D8
Host Mouse
Isotype IgG1 κ
Conjugate Brilliant Violet 510
Target Species Human
Applications FC
Description Hu Desmoglein 2 BV510 6D8 50ug
About Desmoglein-2 and Brilliant Violet 510
Desmoglein-2 This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016]
Brilliant Violet 510 Brilliant™ Violet 510 (BV510) is a green-emitting non-tandem polymer fluorophore that can be excited by the 405 nm Violet laser and collected using a 510/50 bandpass filter. BV510 has an excitation peak at 405 nm and an emission peak at 510 nm, and is similar to StarBright Violet 515 (Bio-Rad). BV510 is most often used in flow cytometry due to its improved signal-to-noise over alternatives like V500 and AmCyan. This dye is part of the Brilliant™ Violet dye line. BV510 and BV480 are the only dyes in the Brilliant™ Violet dye family that are not tandem fluorophores based off the BV421 polymer core, but they have nearly the same maximum excitation.
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Brilliant Violet 510 Excitation and Emission Spectra