CD105 / Brilliant Violet 711 / SN6h (also known as SN6H; G4-2C2)

Product Details
Supplier BD Biosciences
Catalog #: 753544 (View supplier product page)
Size 50 μg
Price $524.00
Antigen CD105
Clone SN6h (also known as SN6H; G4-2C2)
Host Mouse
Isotype IgG1 κ
Conjugate Brilliant Violet 711
Target Species Human
Applications FC
Description Hu CD105 (Endoglin) BV711 SN6H 50ug
About CD105 and Brilliant Violet 711
CD105 This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
Brilliant Violet 711 Brilliant™ Violet 711 (BV711) is a red-emitting tandem fluorophore that can be excited by the 405 nm Violet laser and collected using a 710/50 bandpass filter. BV711 has an excitation peak at 405 nm and an emission peak at 711 nm. BV711 exhibits a medium level of brightness and is most often used in flow cytometry, specifically, it is an alternative to nanocrystals used for intracellular flow. This dye is part of the Brilliant™ Violet dye line of fluorescent polymers. Brilliant™ Violet 421 polymer is employed as the donor molecule in a series of tandem dyes with acceptor molecules emitting at various points across the visible light spectrum. The Brilliant™ Violet dyes are a superior alternative to QDot nanocrystals and similar to SuperNova dye from Beckman Coulter and StarBright dyes from Bio-Rad.
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Brilliant Violet 711 Excitation and Emission Spectra