CD30L / RealYellow 586 / RM153

Product Details
Supplier BD Biosciences
Catalog #: 753155 (View supplier product page)
Size 50 μg
Price $272.00
Antigen CD30L
Clone RM153
Host Rat
Isotype IgG2b κ
Conjugate RealYellow 586
Target Species Mouse
Applications FC
Description Ms CD153 RY586 RM153 50ug
About CD30L and RealYellow 586
CD30L The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
RealYellow 586 BD Horizon RealYellow 586 (RY586) is a bright, yellow emitting dye used in flow cytometry. This fluorophore is excited optimally by the 561 laser and is similar in its emission properties to PE, but interestingly, RY586 shows minimal cross-laser excitation with the 488 laser and can be used in spectral flow cytometry panels concurrently with PE (as stated by supplier).
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RealYellow 586 Excitation and Emission Spectra