Perforin / DyLight 594 / B-D48

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-14581DL594 (View supplier product page)
Size 100 μl
Price $429.00
Antigen Perforin
Clone B-D48
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 594
Target Species Human
Applications WB, FC, ELISA, IHC
Description Perforin Antibody (B-D48) [DyLight 594]
About Perforin and DyLight 594
Perforin This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]
DyLight 594 DyLight™ 594 has an excitation peak at 593 nm and an emission peak at 618 nm and is spectrally similar to Alexa Fluor™ 594 and Texas Red. DyLight™ 594 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 594 Excitation and Emission Spectra