CD49f / DyLight 550 / MP4F10

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB1350L (View supplier product page)
Size 500 μl
Price $759.00
Antigen CD49f
Clone MP4F10
Host Mouse
Isotype IgG2b
Conjugate DyLight 550
Target Species Human
Applications FC, IHC
Description Integrin alpha 6/CD49f Antibody (MP4F10) [DyLight 550]
About CD49f and DyLight 550
CD49f The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
DyLight 550 DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 550 Excitation and Emission Spectra