IL-6 / DyLight 488 / B-E8

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-14588G (View supplier product page)
Size 100 μl
Price $399.00
Antigen IL-6
Clone B-E8
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 488
Target Species Human
Applications FC, ELISA
Description IL-6 Antibody (B-E8) [DyLight 488]
About IL-6 and DyLight 488
IL-6 This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, Aug 2020]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra