IL-13 / Alexa Fluor 532 / B-B13

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-14573AF532 (View supplier product page)
Size 100 μl
Price $409.00
Antigen IL-13
Clone B-B13
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 532
Target Species Human
Applications FC, ELISA
Description IL-13 Antibody (B-B13) [Alexa Fluor® 532]
About IL-13 and Alexa Fluor 532
IL-13 This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
Alexa Fluor 532 Alexa Fluor™ 532 (AF532, Alexa 532) has an excitation peak at 532 nm and an emission peak at 554 nm, and is spectrally similar to Cy®3 (GE Healthcare), TRITC, iFluor® 514 (ATT Bioquest) and iFluor® 546 (ATT Bioquest). Many flow cytometers are equipped with 532nm lasers, so while Alexa 532 can be used for flow cytometry, PE is more commonly used due to its brightness and spectral characteristics. This dye is commonly used for fluorescence microscopy applications.
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Alexa Fluor 532 Excitation and Emission Spectra