IL-12/IL-23 (p40) / Alexa Fluor 750 / B-P24

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-14601AF750 (View supplier product page)
Size 100 μl
Price $399.00
Antigen IL-12/IL-23 (p40)
Clone B-P24
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 750
Target Species Human
Applications FC, ELISA
Description IL-12/IL-23 p40 Antibody (B-P24) [Alexa Fluor® 750]
About IL-12/IL-23 (p40) and Alexa Fluor 750
IL-12/IL-23 (p40) This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008]
Alexa Fluor 750 Alexa Fluor™ 750 (AF750, Alexa 750) has an excitation peak at 749 nm and an emission peak at 775 nm, and is spetrally similar to Cy®7 (GE Healthcare), APC-Fire™ 750 (BioLegend), CF®®750 (Biotium), DyLight™ 750 (ThermoFisher Scientific), iFluor® 750 (ATT Bioquest) and iFluor® 790 (ATT Bioquest). Alexa 750 is often used as a tandem fluorophore in flow cytometry or used on its own in fluorescence microscopy, in-vivo fluorescence microscopy or super-resolution microscopy applications.
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Alexa Fluor 750 Excitation and Emission Spectra