EphB2 / PE / 512012
EphB2 / PE / 512012
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | FAB467P (View supplier product page) | |
| Size | 100 Tests | |
| Price | $379.00 | |
| Antigen | EphB2 | |
| Clone | 512012 | |
| Host | Rat | |
| Isotype | IgG2a | |
| Conjugate | PE | |
| Target Species | Human, Mouse | |
| Applications | FC | |
| Description | Human/Mouse EphB2 PE-conjugated Antibody |
About EphB2 and PE
| EphB2 | This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015] | |
|---|---|---|
| PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |
Images
|
Detection of EphB2 in COLO 205 Human Cell Line by Flow Cytometry. COLO 205 human colorectal adenocarcinoma cell line was stained with Rat Anti-Human/Mouse EphB2 PE-conjugated Monoclonal Antibody (Catalog # FAB467P, filled histogram) or isotype control antibody (Catalog # IC006P, open histogram). View our protocol for Staining Membrane-associated Proteins. |
Citations
| Additional Sources |
|
|---|
Reviews & Ratings
PE Excitation and Emission Spectra
$379.00
Supplier Page
Supplier Page
