Frizzled-6 / Biotin /
Frizzled-6 / Biotin /
Product Details
| Supplier | Novus Biologicals, a Bio-Techne brand | |
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| Catalog #: | NBP3-18335B (View supplier product page) | |
| Size | 100 μl | |
| Price | $499.00 | |
| Antigen | Frizzled-6 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Biotin | |
| Target Species | Human, Mouse, Rat | |
| Applications | WB, ELISA, ICC/IF | |
| Description | Frizzled-6 Antibody [Biotin] |
About Frizzled-6 and Biotin
| Frizzled-6 | This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.[provided by RefSeq, Aug 2011] |
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Citations
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Reviews & Ratings
Biotin Excitation and Emission Spectra
$499.00
Supplier Page
Supplier Page
