CXCL11 / Alexa Fluor 350 / B-S40

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-18117AF350 (View supplier product page)
Size 100 μl
Price $369.00
Antigen CXCL11
Clone B-S40
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 350
Target Species Human
Applications ELISA
Description CXCL11/I-TAC Antibody (B-S40) [Alexa Fluor® 350]
About CXCL11 and Alexa Fluor 350
CXCL11 Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
Alexa Fluor 350 Alexa Fluor™ 350 (AF350, Alexa 350) has an excitation peak at 346 nm and an emission peak at 442 nm, and is spectrally similar in size, brightness and application to AMCA, DyLight™ 350 and CF®350. Alexa 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 350 Excitation and Emission Spectra