PSMA / APC / 460420
PSMA / APC / 460420
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | FAB4234A (View supplier product page) | |
| Size | 100 Tests | |
| Price | $419.00 | |
| Antigen | PSMA | |
| Clone | 460420 | |
| Host | Mouse | |
| Isotype | IgG2a | |
| Conjugate | APC | |
| Target Species | Human | |
| Applications | FC | |
| Description | Human PSMA/FOLH1/NAALADase I APC-conjugated Antibody |
About PSMA and APC
| PSMA | This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq, Jul 2010] | |
|---|---|---|
| APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Images
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Detection of PSMA/FOLH1/NAALADase I in LNCaP Human Cell Line by Flow Cytometry. LNCaP human prostate cancer cell line was stained with Mouse Anti-Human PSMA/FOLH1/NAALADase I APC-conjugated Monoclonal Antibody (Catalog # FAB4234A, filled histogram) or isotype control antibody (Catalog # IC003A, open histogram). View our protocol for Staining Membrane-associated Proteins. |
Citations
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Reviews & Ratings
APC Excitation and Emission Spectra
$419.00
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