CD268 / DyLight 680 / 9B9

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-80072FR (View supplier product page)
Size 100 μl
Price $599.00
Antigen CD268
Clone 9B9
Host Rat
Isotype IgG2b
Conjugate DyLight 680
Target Species Mouse
Applications FC
Description BAFFR/TNFRSF13C Antibody (9B9) [DyLight 680]
About CD268 and DyLight 680
CD268 B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008]
DyLight 680 DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 680 Excitation and Emission Spectra