CD268 / Alexa Fluor 405 / HuBR9.1
CD268 / Alexa Fluor 405 / HuBR9.1
Product Details
Supplier | Novus Biologicals, a Bio-Techne brand | |
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Catalog #: | NBP2-80061AF405 (View supplier product page) | |
Size | 100 μl | |
Price | $599.00 | |
Antigen | CD268 | |
Clone | HuBR9.1 | |
Host | Mouse | |
Isotype | IgG1 | |
Conjugate | Alexa Fluor 405 | |
Target Species | Human | |
Applications | FC | |
Description | BAFFR/TNFRSF13C Antibody (HuBR9.1) [Alexa Fluor® 405] |
About CD268 and Alexa Fluor 405
CD268 | B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008] | |
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Alexa Fluor 405 | Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
Reviews & Ratings
Alexa Fluor 405 Excitation and Emission Spectra
$599.00
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