CD86 / DyLight 350 / GL-1

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB741D (View supplier product page)
Size 500 μl
Price $769.00
Antigen CD86
Clone GL-1
Host Rat
Isotype IgG2a
Conjugate DyLight 350
Target Species Mouse
Applications WB, FC
Description B7-2/CD86 Antibody (GL1) [DyLight 350]
About CD86 and DyLight 350
CD86 This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra