LSECtin / APC / 845404
LSECtin / APC / 845404
Citations:
(1)
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | FAB2947A (View supplier product page) | |
| Size | 100 Tests | |
| Price | $429.00 | |
| Antigen | LSECtin | |
| Clone | 845404 | |
| Host | Mouse | |
| Isotype | IgG2a | |
| Conjugate | APC | |
| Target Species | Human | |
| Applications | FC, ICC | |
| Description | Human LSECtin/CLEC4G APC-conjugated Antibody |
About LSECtin and APC
| LSECtin | This gene encodes a glycan-binding receptor and member of the C-type lectin family which plays a role in the immune response. C-type lectin receptors are pattern recognition receptors located on immune cells that play a role in the recognition and uptake of both self and non-self glycoproteins as well as mediating cell adhesion, glycoprotein clearance, and cell signaling functions. This gene's protein binds complex-type N-glycans of the viral envelope proteins of Ebola virus, West Nile filovirus, and SARS coronavirus, but not HIV or hepatitis C virus. In mouse, this protein has been shown to recognize activated T-cells and to negatively regulate T-cell receptor-mediated signalling. It also acts as a novel, liver-specific regulator of NK cell-mediated immunity in mouse. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2020] | |
|---|---|---|
| APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Images
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Detection of LSECtin/CLEC4G in Human Mature Dendritic Cells by Flow Cytometry. Human mature dendritic cells were stained with Mouse Anti-Human LSECtin/CLEC4G APC-conjugated Monoclonal Antibody (Catalog # FAB2947A, filled histogram) or isotype control antibody (Catalog # IC003A, open histogram). View our protocol for Staining Membrane-associated Proteins. |
Citations
| PMID 28270408 | ||
|---|---|---|
| Additional Sources |
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Reviews & Ratings
APC Excitation and Emission Spectra
$429.00
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