CD305 / PE / 342219

Citations: (4)
Product Details
Supplier R&D Systems
Catalog #: FAB2664P (View supplier product page)
Size 100 Tests
Price $409.00
Antigen CD305
Clone 342219
Host Mouse
Isotype IgG2b
Conjugate PE
Target Species Human
Applications FC
Description Human LAIR1 PE-conjugated Antibody
About CD305 and PE
CD305 The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
Images
  CD305 PE R&D Systems antibody anti target:Human host:Mouse isotype:IgG2b clone:342219 Detection of LAIR1 in Human Lymphocytes by Flow Cytometry. Human lymphocytes were stained with Mo...

Detection of LAIR1 in Human Lymphocytes by Flow Cytometry. Human lymphocytes were stained with Mouse Anti-Human LAIR1 PE-conjugated Monoclonal Antibody (Catalog # FAB2664P, filled histogram) or isotype control antibody (Catalog # IC0041P, open histogram). View our protocol for Staining Membrane-associated Proteins.

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PE Excitation and Emission Spectra