CD16 / APC / 3G8

Product Details
Supplier Leinco
Catalog #: C6852-100 µg (View supplier product page)
Size 100 μg
Price $139.10
Antigen CD16
Clone 3G8
Host Mouse
Isotype IgG1 κ
Conjugate APC
Target Species Baboon, Chimpanzee, Cynomolgus macaque, Human, Macaque, Marmoset, Rhesus macaque, Squirrel Monkey
Applications FC
Description CD16 antibody, 3G8, recognizes human CD16, also known as low-affinity IgG receptor III (FcgammaRIII). There are two distinct forms of CD16, CD16a (FcgammaRIIIa) and CD16b (FcgammaRIIIb). CD16a is a 50-65 kDa heterooligomeric polypeptide-anchored transmembrane protein expressed by NK cells, macrophages, and subsets of monocytes1. CD16b is a 48 kDa monomeric glycosylphosphatidylinositol (GPI)-anchored protein expressed on neutrophils1. Upon binding to the Fc portion of IgG or IgG-antigen complex, both CD16 isoforms induce signaling cascades resulting in multiple functions, including phagocytosis, cytokine release, proliferation, degranulation, and antibody dependent cell-mediated cytotoxicity (ADCC)2.
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APC Excitation and Emission Spectra