CCL1 / Unconjugated / 148107

Product Details
Supplier Leinco
Catalog #: T459-500 µg (View supplier product page)
Size 500 μg
Price $525.00
Antigen CCL1
Clone 148107
Host Rat
Isotype IgG2b
Conjugate Unconjugated
Target Species Mouse
Applications ELISA, Block/Neutralize
Description Chemokine (C-C motif) ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells that belongs to a family inflammatory cytokines known as chemokines.1 CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with a cell surface chemokine receptor called CCR8.2 CCL1 may play a role in lymphocyte recruitment in bronchial asthma.3
About CCL1 and Purified
CCL1 This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8. [provided by RefSeq, Sep 2014]
Citations
Additional
Sources
Reviews & Ratings
Purified Excitation and Emission Spectra