APE1 Monoclonal / Unconjugated / 12H2

Product Details
Supplier Thermo Fisher Scientific
Catalog #: MA5-45056 (View supplier product page)
Size 100 μl
Price $440.00
Antigen APE1
Clone 12H2
Host Mouse
Isotype IgG2b
Conjugate Unconjugated
Target Species Human, Mouse
Applications FC, IHC, IHC-P, WB
Description APE1 Monoclonal Antibody (12H2)
About APE1 and Purified
APE1 The APEX gene encodes the major AP endonuclease in human cells. It encodes the APEX endonuclease, a DNA repair enzyme with apurinic/apyrimidinic (AP) activity. Such AP activity sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. The AP sites are the most frequent pre-mutagenic lesions that can prevent normal DNA replication. Splice variants have been found for this gene; all encode the same protein. Disruptions in the biological functions related to APEX are associated with many various malignancies and neurodegenerative diseases.[provided by RefSeq, Dec 2019]
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Purified Excitation and Emission Spectra