Mesothelin / Alexa Fluor 647 / EPR19025-42

Product Details
Supplier Abcam
Catalog #: ab252135 (View supplier product page)
Size 100 μl
Price $465.00
Antigen Mesothelin
Clone EPR19025-42
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 647
Target Species Human
Applications FC
Description Recombinant Alexa Fluor® 647 Anti-Mesothelin antibody [EPR19025-42]
About Mesothelin and Alexa Fluor 647
Mesothelin This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra