IL-1 RAcP / APC-Vio770 / REA558

Product Details
Supplier Miltenyi Biotec
Catalog #: 130-129-857 (View supplier product page)
Size 30 tests in 60 µL
Price $170.00
Antigen IL-1 RAcP
Clone REA558
Host Human
Isotype IgG1
Conjugate APC-Vio770
Target Species Human
Applications FC
Description Clone REA558 recognizes the human IL-1RAcP antigen. The IL-1 receptor accessory protein (IL-1RAcP) is the second subunit required to form a functional receptor complex for IL-1α and β, IL-1F6, IL-1F8, IL1-F9, and IL-33 and is necessary to mediate signal transduction. IL-1RAcP is found in a variety of tissues. | Additional information: Clone REA558 displays negligible binding to Fc receptors | | | |
About IL-1 RAcP and APC-Vio770
IL-1 RAcP This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Jul 2018]
APC-Vio770 APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry.
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APC-Vio770 Excitation and Emission Spectra