CD5 / Vio Bright 515 / REA782

Product Details
Supplier Miltenyi Biotec
Catalog #: 130-126-985 (View supplier product page)
Size 30 tests in 60 µL
Price $170.00
Antigen CD5
Clone REA782
Host Human
Isotype IgG1
Conjugate Vio Bright 515
Target Species Human
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC, Mass Cytometry
Description Clone REA782 recognizes the human CD5 antigen, a 67 kDa single-chain transmembrane glycoprotein also known as T1 or Leu-1. It is expressed on most thymocytes, the majority of peripheral T cells, a subpopulation of B cells, and B cell chronic lymphocytic leukemia (B-CLL) cells. CD5 is a receptor for the B cell antigen CD72 and plays a role in T cell activation. | Additional information: Clone REA782 displays negligible binding to Fc receptors.
About CD5 and Vio Bright 515
CD5 This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes and a subset of B lymphocytes. The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2016]
Vio Bright 515 Vio®Bright® B515 from Miltenyi has an excitation peak at 488 nm and an emission peak at 514. It is comparable to BB515 in flow cytometry.
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Vio Bright 515 Excitation and Emission Spectra