Mannose Receptor / APC / DCN228

Citations: (1)
Product Details
Supplier Miltenyi Biotec
Catalog #: 130-124-012 (View supplier product page)
Size 30 tests in 60 µL
Price $150.00
Antigen Mannose Receptor
Clone DCN228
Host Mouse
Isotype IgG1,κappa
Conjugate APC
Target Species Human
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
Description The mannose receptor (MR), also known as macrophage MR or CD206, is a 162–175 kDa type I membrane protein. It contains an N-terminal cystein-rich domain and eight C-type lectin-like domains (CTLDs), beside a transmembrane and a cytoplasmic domain. CD206 is expressed by macrophages, dendritic cells, and subsets of endothelial cells, but not on monocytes. The MR recognizes multiple mainly microbial carbohydrates with mannose, fucose, or N-acetyl glucosamine residues. The MR mediates endocytosis and phagocytosis, linked to antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity.
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APC Excitation and Emission Spectra