CD85a / PE / 222821
CD85a / PE / 222821
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | FAB1806P-100 (View supplier product page) | |
| Size | 100 Tests | |
| Price | $349.00 | |
| Antigen | CD85a | |
| Clone | 222821 | |
| Host | Mouse | |
| Isotype | IgG2a | |
| Conjugate | PE | |
| Target Species | Human | |
| Applications | FC | |
| Description | Human LILRB3/CD85a/ILT5 PE-conjugated Antibody |
About CD85a and PE
| CD85a | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| PE | Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts. |
Images
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Detection of LILRB3/CD85a/ILT5 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) gated on monocytes were stained with Mouse Anti-Human CD14 APC-conjugated Monoclonal Antibody (Catalog # FAB3832A) and either (A) Mouse Anti-Human LILRB3/CD85a/ILT5 PE-conjugated Monoclonal Antibody (Catalog # FAB1806P) or (B) Mouse IgG2A Phycoerythrin Isotype Control (Catalog # IC003P). View our protocol for Staining Membrane-associated Proteins. |
Citations
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PE Excitation and Emission Spectra
$349.00
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