SOCS2 / Unconjugated / 6D3F6

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-16781-20ul (View supplier product page)
Size 20 μl
Price $179.00
Antigen SOCS2
Clone 6D3F6
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications WB, IHC, ICC/IF, IHC-P
Description SOCS-2 Antibody (6D3F6)
About SOCS2 and Purified
SOCS2 This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
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Purified Excitation and Emission Spectra