CLEC12A / PerCP-Cy5.5 / 50C1

Citations: (1)
Product Details
Supplier BioLegend
Catalog #: 353611 (View supplier product page)
Size 25T
Price $176.00
Antigen CLEC12A
Clone 50C1
Host Mouse
Isotype IgG2a κ
Conjugate PerCP-Cy5.5
Target Species Human
Applications FC
Description PerCP/Cyanine5.5 anti-human CD371 (CLEC12A)
About CLEC12A and PerCP-Cy5.5
CLEC12A This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. [provided by RefSeq, May 2011]
PerCP-Cy5.5 PerCP-Cyanine® 5.5 (PerCP-Cy5.5) is a red-emitting tandem fluorophore that was originally designed to make the PerCP fluorophore more stable and increase signal intensity. The donor molecule, PerCP can be excited by the 488-nm blue laser and and transfers energy to the acceptor molecule, Cy5.5, which emitts light that can be captured with a 695/40 nm bandpass filter. PerCP-Cy5.5 has an excitation peak at 482 nm and an emission peak at 695 nm. There are superior alternatives to PerCP and PerCP-Cy5.5 including RealBlue 705 (BD Biosciences), NovaFluor Blue 690 or PerCP-eFluor™ 710.
Images
  CLEC12A PerCP-Cy5.5 BioLegend antibody anti target:Human host:Mouse isotype:IgG2a κ clone:50C1

Human peripheral blood monocytes were stained with CD371 (CLEC12A, clone 50C1) PerCP/Cyanine5.5 (filled histogram), or mouse IgG2a, κ PerCP/Cyanine5.5 isotype control (open histogram).

Citations
PMID 24631154
Additional
Sources
Reviews & Ratings
PerCP-Cy5.5 Excitation and Emission Spectra