HLA E / PE-Cy7 / 3D12
HLA E / PE-Cy7 / 3D12
Citations:
(7)
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 342607 (View supplier product page) | |
| Size | 25T | |
| Price | $159.00 | |
| Antigen | HLA E | |
| Clone | 3D12 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | PE-Cy7 | |
| Target Species | Human | |
| Applications | FC | |
| Description | PE/Cyanine7 anti-human HLA-E |
About HLA E and PE-Cy7
| HLA E | HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| PE-Cy7 | PE-Cyanine®7 (PE-Cy7, RPE-Cy7) is a far red-emitting tandem fluorophore that combines phycoerythrin (PE) and Cy7. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Cy7, which emits light that can be captured with a 780/60 nm bandpass filter. PE-CY7 has an excitation peak at 565 nm and an emission peak at 778 nm, and is a suitable alternative to PE-Vio®770 (Miltenyi) and cFluor BYG781 (Cytek). |
Images
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Human peripheral blood lymphocytes were stained with HLA-E (clone 3D12) PE/Cy7 (filled histogram) or mouse IgG1, κ PE/Cy7 isotype control (open histogram). |
Citations
| PMID 21248048 | ||
|---|---|---|
| PMID 25742660 | ||
| Additional Sources |
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Reviews & Ratings
PE-Cy7 Excitation and Emission Spectra
$159.00
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