SHANK3 / DyLight 650 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-41171C (View supplier product page)
Size 100 μl
Price $499.00
Antigen SHANK3
Clone
Host Rabbit
Isotype IgG
Conjugate DyLight 650
Target Species Human, Mouse
Applications WB, ELISA, IHC, ICC/IF, IHC-P
Description SHANK3 Antibody [DyLight 650]
About SHANK3 and DyLight 650
SHANK3 This gene is a member of the Shank gene family. Shank proteins are multidomain scaffold proteins of the postsynaptic density that connect neurotransmitter receptors, ion channels, and other membrane proteins to the actin cytoskeleton and G-protein-coupled signaling pathways. Shank proteins also play a role in synapse formation and dendritic spine maturation. Mutations in this gene are a cause of autism spectrum disorder (ASD), which is characterized by impairments in social interaction and communication, and restricted behavioral patterns and interests. Mutations in this gene also cause schizophrenia type 15, and are a major causative factor in the neurological symptoms of 22q13.3 deletion syndrome, which is also known as Phelan-McDermid syndrome. Additional isoforms have been described for this gene but they have not yet been experimentally verified. [provided by RefSeq, Mar 2012]
DyLight 650 DyLight™ 650 is a red-emitting fluorophore that excited by the 640 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 650 has an excitation peak at 652 nm and an emission peak at 672 nm, and is spectrally similar to Alexa Fluor™ 647 and Cy5. DyLight™ 650 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 650 Excitation and Emission Spectra