PUMA / Biotin /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB500-230B (View supplier product page)
Size 100 μl
Price $449.00
Antigen PUMA
Clone
Host Rabbit
Isotype IgG
Conjugate Biotin
Target Species Human
Applications WB
Description PUMA Antibody [Biotin]
About PUMA and Biotin
PUMA This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
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Biotin Excitation and Emission Spectra