PUMA / Alexa Fluor 405 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB500-230AF405 (View supplier product page)
Size 100 μl
Price $449.00
Antigen PUMA
Clone
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 405
Target Species Human
Applications WB
Description PUMA Antibody [Alexa Fluor® 405]
About PUMA and Alexa Fluor 405
PUMA This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra