PRDM16 / Biotin /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-77096B (View supplier product page)
Size 100 μl
Price $499.00
Antigen PRDM16
Clone
Host Rabbit
Isotype IgG
Conjugate Biotin
Target Species Human, Mouse
Applications WB, ELISA, IHC, ICC/IF, IHC-P
Description PRDM16/MEL1 Antibody [Biotin]
About PRDM16 and Biotin
PRDM16 The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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Biotin Excitation and Emission Spectra