PD-1 / DyLight 550 / 12A7D7

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-75519R (View supplier product page)
Size 100 μl
Price $449.00
Antigen PD-1
Clone 12A7D7
Host Mouse
Isotype IgG1
Conjugate DyLight 550
Target Species Human, Mouse, Rat
Applications WB, ELISA, IHC, IHC-P
Description PD-1 Antibody (12A7D7) [DyLight 550]
About PD-1 and DyLight 550
PD-1 Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
DyLight 550 DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 550 Excitation and Emission Spectra