Patched 1 / DyLight 488 /
Patched 1 / DyLight 488 /
Product Details
| Supplier | Novus Biologicals, a Bio-Techne brand | |
|---|---|---|
| Catalog #: | NBP2-23623G (View supplier product page) | |
| Size | 100 μl | |
| Price | $449.00 | |
| Antigen | Patched 1 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | DyLight 488 | |
| Target Species | Mouse | |
| Applications | WB | |
| Description | Patched Antibody [DyLight 488] |
About Patched 1 and DyLight 488
| Patched 1 | This gene encodes a member of the patched family of proteins and a component of the hedgehog signaling pathway. Hedgehog signaling is important in embryonic development and tumorigenesis. The encoded protein is the receptor for the secreted hedgehog ligands, which include sonic hedgehog, indian hedgehog and desert hedgehog. Following binding by one of the hedgehog ligands, the encoded protein is trafficked away from the primary cilium, relieving inhibition of the G-protein-coupled receptor smoothened, which results in activation of downstream signaling. Mutations of this gene have been associated with basal cell nevus syndrome and holoprosencephaly. [provided by RefSeq, Aug 2017] | |
|---|---|---|
| DyLight 488 | DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications. |
Citations
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Reviews & Ratings
DyLight 488 Excitation and Emission Spectra
$449.00
Supplier Page
Supplier Page
