Nse2 / Alexa Fluor 647 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-76263AF647 (View supplier product page)
Size 100 μl
Price $499.00
Antigen Nse2
Clone
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 647
Target Species Human, Mouse, Rat
Applications WB, ELISA
Description Nse2 Antibody [Alexa Fluor® 647]
About Nse2 and Alexa Fluor 647
Nse2 This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance. [provided by RefSeq, Mar 2017]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra