MTA2 / DyLight 680 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-76748FR (View supplier product page)
Size 100 μl
Price $499.00
Antigen MTA2
Clone
Host Rabbit
Isotype IgG
Conjugate DyLight 680
Target Species Human, Mouse, Rat
Applications WB, ELISA, IHC, ICC/IF, IHC-P
Description MTA2 Antibody [DyLight 680]
About MTA2 and DyLight 680
MTA2 This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis. [provided by RefSeq, May 2011]
DyLight 680 DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 680 Excitation and Emission Spectra