ITCH / Unconjugated / 7I7B10

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-16669-20ul (View supplier product page)
Size 20 μl
Price $179.00
Antigen ITCH
Clone 7I7B10
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications WB, Knockout Validated
Description ITCH/AIP4 Antibody (7I7B10)
About ITCH and Purified
ITCH This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
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Purified Excitation and Emission Spectra