CD49f / Alexa Fluor 647 / 450-30A

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-64908AF647 (View supplier product page)
Size 100 μl
Price $499.00
Antigen CD49f
Clone 450-30A
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 647
Target Species Human
Applications WB, FC, IHC, IHC-Fr
Description Integrin alpha 6/CD49f Antibody (450-30A) [Alexa Fluor® 647]
About CD49f and Alexa Fluor 647
CD49f The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra