IL-21 R / DyLight 755 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-76739IR (View supplier product page)
Size 100 μl
Price $499.00
Antigen IL-21 R
Clone
Host Rabbit
Isotype IgG
Conjugate DyLight 755
Target Species Human, Mouse, Rat
Applications WB, ELISA, IHC, ICC/IF, IHC-P
Description IL-21R Antibody [DyLight 755]
About IL-21 R and DyLight 755
IL-21 R The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra