IL-21 R / Alexa Fluor 488 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-76739AF488 (View supplier product page)
Size 100 μl
Price $499.00
Antigen IL-21 R
Clone
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 488
Target Species Human, Mouse, Rat
Applications WB, ELISA, IHC, ICC/IF, IHC-P
Description IL-21R Antibody [Alexa Fluor® 488]
About IL-21 R and Alexa Fluor 488
IL-21 R The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra