Prolactin Receptor Monoclonal / DyLight 405 / PRLR/742

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-34712V (View supplier product page)
Size 0.1 ml
Price $519.00
Antigen Prolactin Receptor
Clone PRLR/742
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 405
Target Species Human
Applications WB, FC, IHC-Fr, IHC-P, ICC/IF, ELISA, IP, IHC
Description It recognizes a protein of 70kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.
About Prolactin Receptor and DyLight 405
Prolactin Receptor This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 405 Excitation and Emission Spectra