CD193 / Alexa Fluor 350 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-77065AF350 (View supplier product page)
Size 100 μl
Price $519.00
Antigen CD193
Clone
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 350
Target Species Human, Mouse, Rat
Applications WB, ELISA, IHC, ICC/IF, IHC-P
Description CCR3 Antibody [Alexa Fluor® 350]
About CD193 and Alexa Fluor 350
CD193 The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]
Alexa Fluor 350 Alexa Fluor™ 350 (AF350, Alexa 350) has an excitation peak at 346 nm and an emission peak at 442 nm, and is spectrally similar in size, brightness and application to AMCA, DyLight™ 350 and CF®350. Alexa 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 350 Excitation and Emission Spectra